This is especially true of the ‘Blue People of Kentucky’. They rushed him by ambulance to… They are known as the "Blue Fugates". It was a military doctor and hematologist by the name Madison Cawein, who figured out what was ‘wrong’ with the blue people and treated them. Methemoglobinemia is a blood disorder where there are elevated levels of methemoglobin in the blood. Get Free Guides to Boost Your SAT/ACT Score, Homologous and Analogous Structures: What's the Difference. ACT Writing: 15 Tips to Raise Your Essay Score, How to Get Into Harvard and the Ivy League, Is the ACT easier than the SAT? The blue people in Kentucky began to disappear in the early 20th century as families moved apart and the disease therefore became less common as inbreeding reduced, reported ABC News. Check out this post about cell theory and why it's important and a discussion of enzymes and what they do. In fact an entire family from isolated Appalachia were blue. (John Vibes) The Fugates, a blue-skinned family from the hills of Kentucky has attracted and baffled scientists for generations, although their condition has now been explained as being caused by the disease Methemoglobinemia, which can make a person’s skin blue. This is wonderful, but it could facilitate transmission of the disease when carriers have children together. Also, be sure to note the family lineage that is presented to you in the text, you will need it for part of your assignment. They settled in Troublesome Creek, Kentucky. Benjy is Martin Fugates great-great-great-great grandson. The Fugates, a family that lived in the hills of Kentucky, commonly known as the "Blue Fugates" or the "Blue People of Kentucky", are notable for having been carriers of a genetic trait that led to the blood disorder methemoglobinemia, which causes the appearance of blue-tinged skin. Fast forward to the seventies and Benjamin Stacy has just been born. Deep in the woods of Kentucky, a fiercely private family gave birth to blue-skinned children since the 1800s. Methemoglobin levels over 50% may result in seizures, coma, and death. Yet Facebook groups have enabled the meeting of many people who have mutations in the same gene. Due to their isolation, the Fugates began inter-marrying, which led to a higher likelihood of passing along the met-H gene, and having blue-skinned children. Although the blue people of Kentucky are a real phenomenon that has been well documented and written about in all manner of publications from science journals to mass-market magazines, I really don't want you goofballs loading your cameras and going on a gawking spree, bothering innocent people. Named after an early settler. Cussy is a pack horse librarian and she delivers books to people that live in the mountains of Kentucky. "I'm a hematologist, so something like that perks up my ears," Cawein says, sipping on whiskey sours and letting his mind slip back to the summer he spent "tromping around the hills looking for blue people." Deep in the woods of Kentucky, a fiercely private family gave birth to blue-skinned children since the 1800s. Methemoglobin is a form of hemoglobin that contains the iron Fe3. [8], Benjamin Stacy, born in 1975, is the last known descendant of the Fugates to have been born exhibiting the characteristic blue color of the disorder, though he quickly lost his blue skin tone, exhibiting only blue tinges on his lips and fingertips if he was cold, or agitated. Sit back, relax, and read the amazing but true genetic tale of the Blue People of Kentucky. The doctors were astonished by the color of Benjy’s skin. In an unusual story that involves both genetics and geography, an entire family from isolated Appalachia was tinged blue. The short answer is no, but a more accurate one would be ‘no more’. Haddix is located near the confluen… As time passed, descendants of the family moved out of the area, and new populations moved in, which allowed the Fugates to meet and marry people who did not share their genes at all. The isolation made this difficult, and created a strangely perfect environment for the hereditary disorder to continue. Blue people’s life wasn’t that easy. Jan 25, 2014 - Explore Janice Jordan's board "Blue People of Kentucky", followed by 192 people on Pinterest. The family was from upper Kentucky, and Horsley claimed her mother-in-law’s nails and lips were always blue, and got worse if she were cold, upset, or angry. Oyata Bulaya says: May 17, 2018 at 1:03 am. In the early 1960’s, two blue descendants of the family, Rachel and Patrick Ritchie, met Doctor Madison Cawein III. The disorder is extremely rare. What SAT Target Score Should You Be Aiming For? The Blue People of Kentucky are still discussed, but less is known about. As the story goes, Martin Fugate, a French orphan, settled on the banks of eastern Kentucky's Troublesome Creek around 1820 to claim a land grant. Patrick and Rachel Ritchie, Fugate descendants, were cured by injections of methylene blue. The color of their skin was so shocking for normal people to see, that they chose to stay hidden away from the rest of society in their small community. Benjamin lost his blue coloring within a few weeks. He determined that injections of methylene blue would be able to cure them (more later on why that worked). Jan 25, 2014 - Explore Janice Jordan's board "Blue People of Kentucky", followed by 192 people on Pinterest. Unknown to the couple at the time they both carried a … 017 | Blue People of Kentucky from Southern Oddities on Podchaser, aired Thursday, 14th January 2021. See more ideas about kentucky, blue, appalachia. There were no roads, and the railroad would not reach the area until 1910. Madison Cawein, a hematologist from the University of Kentucky got extremely fond of the rumors and stories about the Blue Fugate family. The Fugates, a family that lived in the hills of Kentucky, commonly known as the "Blue Fugates"[1] or the "Blue People of Kentucky", are notable for having been carriers of a genetic trait that led to the blood disorder methemoglobinemia, which causes the appearance of blue-tinged skin. A Comprehensive Guide. The Blue People Of Kentucky: For almost two centuries, the “blue skinned people of the Fugate family” lived in the areas of Troublesome Creek and Ball Creek in the hills of eastern Kentucky. … It can also arise in patients with kidney disease who have an impaired ability to produce NADH. For a hundred and fifty years, locals in the area of Hazard, Kentucky were stumped by a group of people. Patients then take pills for as long as they wish to continue being not-blue. The most detailed account, "Blue People of Troublesome Creek," was published in 1982 by the University of Indiana's Cathy Trost. Since neither parent had symptoms of methemoglobinemia, they were shocked and confused, and no one could offer an explanation. There is more evidence to this argument but I don't want to waste your time. In the late 1950s, a hematologist named Martin Cawein from the University of Kentucky was fascinated by the stories of the blue Fugate family. Shame, psychological trauma, and discrimination resulted in that the Blue People of Kentucky isolated themselves from the rest of society. The Fugates and their descendants were forced to show the world their history of inter-marriage with their blue skin. The Blue Fugates, sometimes known as the Huntsville subgroup, were well known in the area, and their genetic disorder went unidentified until the mid twentieth century, when the amount of affected people had greatly decreased. Again, they were unable to prove a connection to the Fugates. See more ideas about kentucky, people, medical oddities. Some reports say Martin was not blue but was a carrier of the methemoglobinemia gene. As a result of this weird disorder, they decided to isolate themselves from the community. Neighbors laughed at the family’s blue coloring and most avoided the Fugates. In a diverse gene pool, a recessive trait like this one would have died out quickly, or only been a rare occurrence. He finally found a couplePatrick and Rachel Ritchiewho was willing to participate in his study. Blue People of Kentucky Why the Fugate Family Had Blue SkinA Frenchman arrived in Kentucky in 1820, bringing with him his strange blue skin. Who Are the Blue People of Kentucky? He began hearing rumors about these blue people when he went to work at the University of Kentucky’s Lexington medical clinic in 1960.… The answer is methemoglobinemia. All Blue Fugates were stigmatized due to their unusual appearance. For nearly two centuries, the Fugate family of Kentucky passed their unique characteristic of blue skin from one generation to the next. Martin Fugate, a French orphan, married a woman named Elizabeth around 1820. Infants have naturally lower levels of the enzyme NADH– the same enzyme that prohibits oxygen from traveling in the blood in those who inherit the mutation, and are at a higher risk for developing methemoglobinemia, especially when exposed to nitrates. A sad recent example is the In the 1960s, a young hematologist named Madison Cawein traveled to the region with an aim to cure the blue people of their skin color. Scientists were quite intrigued as to the cause of the blue skin (cyanosis) in the Fugate family. In 1960, he decided to move near Troublesome Creek in the hopes to meet one of them some day. Little did they know that their union would create shades o… I recently took a genetics course this past spring semester and learnt a lot about genetic mutations which can be sex-linked, linked or un-linked. Vitamin C has also been used to reduce cyanosis temporarily. Source – The Mind Unleashed Original source unknown, via ABC News The Blue Fugates are shown in this colorized black and white photo. Mar 14, 2017 - Explore Carol Kline's board "Blue Fugates of Kentucky", followed by 227 people on Pinterest. It’s not likely that this would be permanent, and is also unlikely to cause the "blue all over" look of the Fugates. Some use of antibiotics can lead to methemoglobinemia, as can use of local anesthetics and the ingestions of nitrates. Cawein ran tests, and discovered that the levels of methemoglobin in the blood were extremely high. The Fugates, a family that lived in the hills of Kentucky, commonly known as the "Blue Fugates" or the "Blue People of Kentucky", are notable for having been carriers of a genetic trait that led to the blood disorder methemoglobinemia, which causes the appearance of blue-tinged skin. Read the following article on the Blue Family in Kentucky. Samuel Haddix, a native… Though inter-marriage was not rare or necessarily discouraged at the time in rural Kentucky, it did lead to some unfortunate stereotypes about the people of Appalachia, a narrative the Fugates couldn’t shed due to their outward appearance. Their ancestral line began six generations earlier with a French orphan, Martin Fugate, who settled in Eastern Kentucky. In the 1800s a family of blue-skinned people fascinated and, as we might imagine given the times, horrified many people in the state of Kentucky. The doctor hiked through the Appalachian hills, on a mission to find the famous blue people of Kentucky. Samuel Haddix, a native of Virginia. They settled in Troublesome Creek, Kentucky. He made frequent trips to Hazard in the hope of finding some blue people. Shame, psychological trauma, and discrimination resulted in that the Blue People of Kentucky isolated themselves from the rest of society. Martin Fugate and Elizabeth Smith[2] who had married and settled near Hazard, Kentucky, around 1820, were both carriers of the recessive methemoglobinemia (met-H) gene. I enjoy historically based novels because I can see into a world different from my own. (John Vibes) The Fugates, a blue-skinned family from the hills of Kentucky has attracted and baffled scientists for generations, although their condition has now been explained as being caused by the disease Methemoglobinemia, which can make a person’s skin blue. Hence this discrimination resulted in that the Blue family isolated themselves from the rest of the people. They are known as the "Blue Fugates". . March 7, … Blue People Look for Genetic Connection to Kentucky Fugates Rare genetic condition gives people blue skin color. Check out our top-rated graduate blogs here: © PrepScholar 2013-2018. Not myth or legend; The Blue People of Kentucky were an isolated enclave of Appalachian people who lived with an embarrassing skin discoloration until a young hematologist took notice and found a solution. Another woman named Jennifer L. Adams Horsley of Indiana believed her mother-in-law had the condition as well. Haddix, Kentucky.. is an unincorporated community and coal town in Breathitt County, Kentucky. Reference: Adapted from an article in Science 82, November 1982 by Cathy Trost For more information on the Blue Fugates of Kentucky go to google.com and type in blue fugates blue troublesome creek was white to connect it was blue people of kentucky. Old color photographs of the family clearly show about half of the members to have a distinct cobalt blue skin color, while the other have regular white skin color. The Blue People of Kentucky aren’t limited to Benjy and Luna. When the “Pandemic of 2020” hit I was reading “The Book Woman of Troublesome Creek.” The book is a story about a young woman who lived in the Appalachian Mountains of Eastern Kentucky during the 1930s. Typically, the blue is isolated to one part of the body. What if these Blue people, or even the Melungeons of eastern Kentucky (who by the way, migrated from the Carolinas in their own lore) could be the lost piece of this Atlantean Colonial system. THE BLUE PEOPLE OF TROUBLESOME CREEK The story of an Appalachian malady, an inquisitive doctor, and a paradoxical cure. Doctor Ayalew Tefferi of the Mayo Clinic told ABC news in 2013 that “You almost never see it.” Kerry Green, an Oklahoma native, has a severe version of the disease that affects his health, and his body has trouble carrying oxygen to his organs. Life for the Blue people of Kentucky was not a dance on roses. Ask questions; get answers. Very few people knew they even existed, until today. [2][6] He found that a report from 1960 by a public health doctor, E. M. Scott, who published in the Journal of Clinical Investigation his research on the phenomenon among native Alaskans, based on the theory that a deficiency of the enzyme diaphorase is the cause of the oxygen deficiency in the red blood cells, causing the blood to appear brown, which in turn made the skin of those affected appear blue. Share. This is why the Fugate family was affected so frequently. The Blue People of Kentucky and the Pack Horse Library Project are both fascinating historical realities that are barely understood today. With two parents that were potentially carriers, or affected themselves, it increased the likelihood of having children who inherited the disorder or were unaffected carriers. His passion and desire to become popular in the books of history made him unravel the mystery of the Blue people in Kentucky. The Fugates also showed the importance of access to medicine and medical information. 00:10:34 - Haddix, Kentucky.. is an unincorporated community and coal town in Breathitt County, Kentucky. Exposure to the oxidizing drugs can overwhelm the system, and convert hemoglobin into methemoglobin. Because of their family and their prominence as Blue People of Kentucky, patients today, especially blue-syndrome babies, have the benefit of information about methemoglobinemia and options for cures and treatments. Samuel Haddix, a native… Unbeknownst to the couple, they were coincidentally both carriers of a recessive gene (met-H) that caused methemoglobinemia, which can tint the skin of sufferers blue. Are there really blue skinned people living in Kentucky? The Fugates’ son, Zacariah, married Elizabeth’s sister/his aunt. The 5 Strategies You Must Be Using to Improve 4+ ACT Points, How to Get a Perfect 36 ACT, by a Perfect Scorer. What if these Blue people, or even the Melungeons of eastern Kentucky (who by the way, migrated from the Carolinas in their own lore) could be the lost piece of this Atlantean Colonial system. 00:10:34 - Haddix, Kentucky.. is an unincorporated community and coal town in Breathitt County, Kentucky. He was born in a hospital near Hazard, Kentucky. Madison Cawein began hearing rumors about the blue people when he went to work at the University of Kentucky's Lexington medical clinic in 1960. Diagnosis and Treatment of the Blue Fugates of Kentucky. The Fugates probably had a deficiency in the enzyme called cytochrome-b5 methemoglobin reductase, which is responsible for recessive congenital methemoglobinemia. As ABC details, Dr. Madison Cawein III set out to find a group of blue people.At first blush, this mission smacks pure lunacy, or even purer cocaine.Did this guy get high and convince himself he was Gargamel searching for Smurfs?Shockingly not. The Fugate family of Kentucky has been known for their blue skin color for generations. Named after an early settler. But how on earth can someone get blue skin? Twitter. in the right direction in my search for the mysterious Blue People of the Cherokee Legends. Facebook . Why Are They Blue? Blood is also likely to be a chocolate brown color instead of bright red in patients with methemoglobinemia. As the Fugates spread out geographically over time and generations, the disease was less likely to be passed on but also harder to track. The area was extremely rural and isolated in the nineteenth century. As time went on, fewer and fewer people with the condition were born and the blue skin condition disappeared altogether. See more ideas about kentucky, people, medical oddities. Benjamin’s father remembered that the last blue Fugate before Benjamin had been his grandmother, Luna, who was a dark blue her whole life. When he was born, Benjamin was so blue he was almost purple, which caused panic at the hospital. Hemoglobin is the protein in red blood cells that is responsible for transporting oxygen throughout the body, and raised levels of methemoglobin happen when the mechanisms that defend against oxidative stress are overwhelmed by Fe3. "Blue-skinned family baffled science for 150 years", article on the Fugates of Appalachia, an extended family of blue-skinned people, "Fugates of Kentucky: Skin Bluer than Lake Louise", "Blue People Look for Genetic Connection to Kentucky Fugates", https://en.wikipedia.org/w/index.php?title=Blue_Fugates&oldid=988865350, Creative Commons Attribution-ShareAlike License, This page was last edited on 15 November 2020, at 18:44. Stemming from French immigrant Martin Fugate, who moved to Kentucky in 1820, the blue people were to become legends in their own right. There are no known blue-skinned Fugates today. One of the most recent descendents that was born blue was Benjamin “Benjy” Stacy. He married a red-haired American named Elizabeth Smith with a very pale complexion. By SUSAN DONALDSON JAMES. In 2019, the novel The Book Woman of Troublesome Creek, by Kim Michele Richardson, described a fictional version of the Fugate family during the Great Depression. Martin and Elizabeth had seven children, four of whom had blue skin. She worked in book publishing for several years, and believes that books can open up new worlds. Email. Source – The Mind Unleashed He injected both patients with methylene blue, and nurse Ruth Pendergrass noted that they “changed color before her eyes.” Both patients continued to take methylene pills to make sure their blue color didn’t return. The Blue People of Kentucky and the Pack Horse Library Project are both fascinating historical realities that are barely understood today. The color of their skin was so shocking for normal people to see, that they chose to stay hidden away from the rest of society in their small community. Others might think of the Blue Man Group or even the Smurfs. This feature of a blue skin shade is with the Fugate family who were of French Huguenot descent, with the original immigrant ancestor coming over from France in about 1820. Kept to have plenty of troublesome worksheet alaskans scott speculated these were reported to achieve a situation that turned his aunt bessie fugate, learn more travelers to understand. The year is 1936 and the setting takes place in the Appalachian Mountains into the woods of Troublesome Creek. Total body cyanosis, like that of the Fugates, is rare for this disorder. Story Behind “The Blue People in Kentucky” – Blue Fugates Family. Our new student and parent forum, at ExpertHub.PrepScholar.com, allow you to interact with your peers and the PrepScholar staff. Martin Fugate, a French orphan, married a woman named Elizabeth around 1820. Thus, the family continued passing down the trait. With two carrier parents, a child would have a ¼ chance of being born with methemoglobinemia, a 2/4 chance of being an unaffected carrier, and a ¼ chance of not inheriting the gene at all. Martin Fugate came to Troublesome Creek (near Hazard) from France in 1820 and… well… he happened to be blue. WhatsApp. The Fugates, a family that lived in the hills of Kentucky, had the hereditary form. As ABC details, Dr. Madison Cawein III set out to find a group of blue people.At first blush, this mission smacks pure lunacy, or even purer cocaine.Did this guy get high and convince himself he was Gargamel searching for Smurfs?Shockingly not. Image: via NClark Illustration of Martin Fugate and his family. She loves reading, the outdoors, and learning about new things. Green cannot definitively trace his lineage back to the Fugates, but suspects he inherited the disorder from his father, whom he never met. Which suggests that the Blue people of Kentucky are not just an urban legend. The ancestral line began with a French orphan, Martin Fugate, who settled in Eastern Kentucky. Then it converts from hemoglobin to methemoglobin. Unfortunately, this meant that other families in nearby communities were less likely to marry into the Fugate family for fear that they would also have blue-skinned children. [7] He eventually published his research in the Archives of Internal Medicine in 1964. Get the latest articles and test prep tips! Apparently, their ancestral line began six generations earlier with a French orphan, Martin Fugate. The College Entrance Examination BoardTM does not endorse, nor is it affiliated in any way with the owner or any content of this site. Many people wondered if there was someone that heard about these people and help them and actually there was. The Blue people of Kentucky were segregated in the 1930s much the same as those who had anything but white skin. The only other families nearby were related to Elizabeth. Cawein had just started work at the University of Kentucky’s Lexington medical clinic. THE BLUE PEOPLE OF TROUBLESOME CREEK The story of an Appalachian malady, an inquisitive doctor, and a paradoxical cure. Though these blue skin people were accepted socially in some places, in others they were discriminated against, pointed to as a warning against inter-marriage, and held up as a symbol of rural stereotypes. The doctor hiked through the Appalachian hills, on a mission to find the famous blue people of Kentucky. [5], It has been speculated that some other Americans who inherited methemoglobinemia may also have had Fugate ancestors, but searches for direct links have so far proved inconclusive.[6]. Ngozika. Unbeknownst to the couple, they were coincidentally both carriers of a recessive gene (met-H) that caused methemoglobinemia, which can tint the skin of sufferers blue. [5], Cawein treated the family with methylene blue, which eased their symptoms and reduced the blue coloring of their skin. Very few people knew they even existed, until […] Carrie holds a Bachelors in Writing, Literature, and Publishing from Emerson College, and is currently pursuing an MFA. Ask below and we'll reply! With regard to the other blue people of Kentucky; following the opening up of rail tracks and motorable roads, they began to move away to other communities and inter-marry with people without the gene. hbspt.cta.load(360031, '4efd5fbd-40d7-4b12-8674-6c4f312edd05', {}); Have any questions about this article or other topics? Named after an early settler. This will usually go away on its own. What ACT target score should you be aiming for? Be sure to jot down important information as to how these people turned blue. Kentucky has … blue people? This decreased the likelihood of having children that had met-H. A man named Paul Karason famously turned blue after getting argyria, as a result of drinking colloidal silver for alleged health benefits. Related Love Makes Us More Intelligent, According to Neuroscience. You can also explore how animals are biologically related to each other in Homologous and Analogous Structures: What's the Difference? The ailment, which was later revealed to be a symptom of methemoglobinemia, was contained mostly to descendants of the Fugate family of Troublesome Creek, and a related family in nearby Ball Creek. Richardson’s novel, which she began writing in 2016 and published in May, is a first-person narrative about a woman named Cussy Mary Carter, who has a rare genetic condition that makes her skin appear blue (based on the real-life blue-skinned people of Kentucky). Those who are otherwise healthy with levels under 15% may exhibit minor symptoms or none at all. The Fugates and the met-H gene they passed for generations can teach us a valuable lesson about genetics and understanding disease. Enjoy historically based novels because I can see into a world different from my.. 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